Clinical and Morphological Spectrum of Hydatid disease – A 14 years hospital based study

Authors

  • Dilasma Ghartimagar Department of Pathology Manipal Teaching Hospital Manipal College of Medical Sciences Pokhara
  • Arnab Ghosh Department of PathologyManipal Teaching HospitalManipal College of Medical SciencesPokhara
  • Manish Kiran Shrestha Department of RadiologyManipal Teaching HospitalManipal College of Medical SciencesPokhara
  • O P Talwar Department of Pathology Manipal Teaching Hospital Manipal College of Medical Sciences Pokhara
  • Brijesh Sathian Department of Community Medicine Manipal Teaching Hospital Manipal College of Medical Sciences Pokhara

DOI:

https://doi.org/10.31729/jnma.1351

Abstract

Background and objective

 Hydatid disease is endemic in sheep and cattle-raising areas world wide. Its prevalence is high in Nepal. The study was carried out to determine the clinical, radiological and pathological presentations of hydatid disease.

Method

This was a retrospective study of all hydatid disease cases reported in Department of Pathology, from August 1996 to July 2010. All the clinical, radiological and pathological data were collected and collated.

Result  

 A total of 51 cases of hydatidosis were studied. Patients presented with related symptoms in 47 cases, 92.16% with CI (84.78,99.54) and asymptomatic in 4 cases, 7.84% with CI (0.46, 15.22). Involvement of liver and lung was found in 35 cases (68.63%) and 10 cases (19.61%) respectively. Involvement of other organs like kidney, pelvis and broad ligament were seen in 6 of the cases.  29 cases, 56.86% with CI ( 43.2, 70.46) had solitary cyst while rest of the cases had multiloculated cyst. All cases had radiological correlation and histopathological confirmation. 

Conclusion

Most cases presented with organ related vague symptoms, however it should be considered as a differential diagnosis especially in asymptomatic cases and cases with unusual sites. Imaging studies is useful in preoperative diagnosis and postoperative histopathology is confirmatory. A multi centric hospital based study will help to decrease the incidience.

References

1. Siracusano A, Teggi A, Ortona E. Human Cystic Echinococcosis: Old Problems and New Perspectives. Interdiscip Perspect Infect Dis 2009; 2009: 474368. Available from URL: www.ncbi.nlm.nih.gov/emc/articles/PMC2771156/
2. Mandell GL, Douglas RG, Bennett JE, Dolin R, editors. Mandell, Douglas and Bennett's principles and practice of infectious diseases. 5th ed. Philadelphia:Churchill Livingstone; 2000. p. 2956-65.
3. White AC Jr, Weller PF. Cestodes. In: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL, editors. Harrison’s Internal Medicine. 17th ed. Mc Graw Hill Companies; 2008.vol 1 p.1338-40.
4. King C. Cestodes (tapeworms). In: Mandell G, Bennett J, Dolin R, editors. Principles and practices of infectious diseases. 5th ed. New York: Churchill Livingstone; 2000. p. 633-40
5. Gottstein B, Reichen J. Echinococcosis/ Hydatidosis. In: Cook G, Zumla A, editor. Manson’s Tropical Diseases 21st ed. London: Elsevier Science, Health Sciences Division; 2003. p.1561-77.
6. Kak VK, Mathuriya SN. Hydatid disease of the nervous system. In: Chopra JS, Sawhney BI, editors. Neurology in tropics. London: Churchill Livingstone; 1999. p. 244-58.
7. Gabriele F, Bortoletti G, Conchedda M, Palmas C, Ecca AR. Epidemiology of hydatid disease in the Mediterranean basin with special reference to Italy. Parassitologia 1997 Mar; 39(1):47-52.
8. Ito A, Okamoto M, Ishiguro T, Ma L, Suzuki H, Yasui A. Short report: An imported case of cystic echinococcosis in Japan diagnosed by imaging and serology with confirmation of Echinococcus granulosus-specific DNA sequences. Am J Trop Med Hyg. 1998 Jun; 58(6):790-2.
9. Dahnert W. Radiology Review Manual. 6th ed. New York: Lippincott Williams and Wilkins; 2007. p. 710-2
10. Dahnert W. Radiology Review Manual. 6th ed. New York: Lippincott Williams and Wilkins; 2007. p. 500-1
11. Chatterjee KD . Parasitology 12 Ed . Calcutta : Chatterjee Medical Publishers ; p.107-32
12. Aribas OK , Kanat F, Gormus N, Turk E. Pleural complications of hydatid disease. Thorac Cardiovasc Surg 2002;123:492-7
13. Ali M, Mahmood K, Khan P. Hydatid cysts of the brain. J Ayub Med Coll Abbottabad 2009;21(3):21-3
14. Burgos R, Varela A, Castedo E, Roda J, Montero CG, Serrano S. Pulmonary hydatidosis: surgical treatment and follow-up of 240 cases. European Journal of Cardio-thoracic Surgery 1999;16: 628-35
15. Cavusoglu H, Tuncer C, Ozdilmac A, Aydin Y. Multiple Intracranial Hydatid Cysts in a Boy. Turkish Neurosurgery 2009; 19: 203-7
16. Scherer K, Gupta N, Caine WP, Panda M. Differential Diagnosis and Management of a Recurrent Hepatic Cyst: A Case Report and Review of Literature. J Gen Intern Med 2009;24(10):1161–5
17. Wani I, Wani S, Baba A, Khanday Z, Bhat N, Shera A et al. Primary calcified hydatid of spleen: a case report. Internet Journal of Medical Update 2010;5(2):68-70
Available from URL: http://www.akspublication.com/ijmu
18. Ghoshal AG, Sarkar S, Saha K, Sarkar U, Kundu S, Chatterjee S, Kundu S. Hydatid Lung Disease: An Analysis of Five years Cumulative Data from Kolkata. JAPI 2012; 60:12-6.
19. Kir A, Baran E. Simultaneous operation for hydatid cyst of right lung and liver. Thorac Cardiovasc Surg. 1995 Feb;43(1):62-4.
20. Tora M, Atasalihib A, Altuntasa N, Sulua E, Senola T, Kirb A . Review of Cases with Cystic Hydatid Lung Disease in a Tertiary Referral Hospital Located in an Endemic Region: A 10 Years’ Experience. Respiration 2000;67:539-42.
21. Mood BS, Fazaeli A, Mokhtari S, Fifteen years experience with pulmonary hydatidosis in Zahedan, Iran. Iranian J Parasitol 2007; 2(4):7-11
22. Montazeri V, Sokouti M, Rashidi MR. Comparison of Pulmonary Hydatid Disease betweenChildren and Adults. Tanaffos 2007; 6(1): 13-8
23. WHO Informal Working Group 1. International classification of ultrasound images in cystic echinococcosis for application in clinical and field epidemiological settings. Acta Tropica 2003;85: 253- 61
24. Guntz M, Coppo B, Lorimier G, Cronier P. Hydatid cysts of the liver appearing late (10 to 22 years) after surgical treatment of pulmonary hydatidosis. Physiopathologic problems . J Chir (Paris). 1990 Aug-Sep;127(8-9):375-81.
25. Altinörs N, Senveli E, Dönmez T, Bavbek M, Kars Z, Sanli M. Management of problematic intracranial hydatid cysts. Infection. 1995 Sep-Oct;23(5):283-7
26. Brown RA, Millar AJ, Steiner Z, Krige JE, Burkimsher D, Cywes S. Hydatid cyst of the pancreas a case report in child. Eur J Pediatric Surgery 1995;5:121-4.
27. McManus DP, Thompson RC. Molecular epidemiology of cystic echinococcosis. Parasitology 2003;127S: 37-51
28. Kant S, Singh R, Bhatia RS, Sanjay. Unusual presentation of hydatid disease. The Internet Journal of Pulmonary Medicine 2008;10(1). Available from URL:
www.ispub.com/journal/the_internet_journal_of_pulmonary_medicine
29. Marwah S, Kamal H, Marwah N. Laparoscopic management of a large primary retroperitoneal hydatid cyst. Clinical Journal of Gastroenterology 2010;3(4): 230-2.
30. PAIR: puncture, aspiration, injection, re-aspiration: an option for the treatment of cystic echinococcosis. Geneva, World Health Organization, 2001. Available from URL: whqlibdoc.who.int/hq/2001/WHO_CDS_CSR_APH_2001.6.pdf

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Published

2013-06-30

How to Cite

Ghartimagar, D., Ghosh, A., Shrestha, M. K., Talwar, O. P., & Sathian, B. (2013). Clinical and Morphological Spectrum of Hydatid disease – A 14 years hospital based study. Journal of Nepal Medical Association, 52(190). https://doi.org/10.31729/jnma.1351

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