Thyrotoxic Periodic Paralysis with Hypokalemia in an Adult Male from Nepal: A Case Report

  • Sabina Khadka Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
  • Indu K.C. Department of Medicine, Shree Birendra Hospital, Chhauni, Kathmandu, Nepal
  • Rabindra Jang Rayamajhi Department of Medicine, Shree Birendra Hospital, Chhauni, Kathmandu, Nepal
  • Pravakar Dawadi Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
  • Pravash Budhathoki Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
Keywords: hyperthyroidism; hypokalemia; muscle paralysis; thyrotoxic periodic paralysis.

Abstract

Thyrotoxic periodic paralysis is rare complication of hyperthyroidism characterized by the sudden onset of hypokalemia and muscle paralysis. It is typically present in young Asian males. There are very few literatures regarding the occurrence of thyrotoxic hypokalemic periodic paralysis in Nepal. We reported a case of a 35-year-old male presented with the chief complaints of weakness of all four limbs of 1 day duration. He was diagnosed as a case of hyperthyroidism in the past, received treatment for 6 months and left medications on his own 6 months ago. Evaluation during admission revealed severe hypokalemia with serum potassium level 1.3mEq/l and high serum Triiodothyronine (>20.00µg/L) and low serum Thyroid Stimulating Hormone (<0.01µg/L). Potassium supplements resolved muscle weakness and the patient was restarted with anti-thyroid drugs. Hence, hypokalemic paralysis is a reversible cause of paralysis and high index of suspicion as well as timely interventions are required to prevent potential harm.

Published
2019-12-31
How to Cite
Khadka, S., K.C., I., Rayamajhi, R. J., Dawadi, P., & Budhathoki, P. (2019). Thyrotoxic Periodic Paralysis with Hypokalemia in an Adult Male from Nepal: A Case Report. Journal of Nepal Medical Association, 57(220). https://doi.org/10.31729/jnma.4763
Section
Case Reports