ENDOMETRIAL STUDY OF ABNORMAL UTERINE BLEEDING IN WOMEN AT 45 YEARS AND ABOVE

Abstract

ABSTRACT
The study is done to know the causes for the abnormal uterine bleeding in perimenopausal women at
Chitwan valley and to compare the histopathological findings between the pre-menopausal and
postmenopausal women. Retrospective analysis of patients who have had abnormal bleeding during a period
of one and a half years' from January 2000 to June 2001 in Department of Gynaecological Oncology of BP
Koirala Memorial Cancer Hospital (BPKMCH), Chitwan, Nepal. There were total sixty women (aged 45
years and above) having abnormal bleeding managed at BPKMCH. A total of sixty patients were studied.
Majority (57%) of them was postmenopausal ladies presented with abnormal vaginal bleeding. The age
range was 45 to 81 years. Only 37% had pathological bleeding including malignancies and only about 17%
had malignancies. Malignant diseases were found in 7.7% cases in the pre-menopausal ladies whereas it
was 23.4%, almost three times higher, in the post-menopausal ladies. Carcinoma of the cervix and of the
endometrium occurred with increasing frequency with increasing age in this study. So, a thorough work-up
is needed for the elderly women presenting with an abnormal vaginal bleeding especially to rule out
malignancies.

Key Words: endometrial biopsy, endometrial cancer, postmenopausal bleeding.