Multidrug Resistant Escherichia coli among Urinary Samples of Patients with Urinary Tract Infection in the Microbiology Department of a Tertiary Care Center: A Descriptive Cross-Sectional Study

Authors

  • Raina Chaudhary Department of Microbiology, Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
  • Manoj Pradhan Department of Microbiology, Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
  • Sabita Bhatta Department of Microbiology, Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal
  • Sabnum Shrestha Kantipur College of Medical Sciences, Sitapaila, Kathmandu, Nepal
  • Nabaraj Adhikari Central Department of Microbiology, Tribhuvan University Institute of Science and Technology, Kirtipur, Kathmandu, Nepal
  • Yengkokpam Ibotomba Singh Department of Microbiology, Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal

DOI:

https://doi.org/10.31729/jnma.8160

Keywords:

antibiotics; Escherichia coli; urinary tract infection.

Abstract

Introduction: Urinary Tract Infection one of the most common and manageable infections still holds its position as a major public health issue worldwide due to an increase in the number of multidrug resistant bacteria. This study aims to find out the prevalence of multidrug resistant Escherichia coli among urinary samples of patients with urinary tract infections in the microbiology Department of a tertiary care center.

Methods: A descriptive cross-sectional study was carried out at a tertiary care centre from 8 August 2018 to 9 January 2019. Ethical approval was received from the Institutional Review Committee (Reference number: 123/2018). Clinically suspected cases of urinary tract infection were included in this study. A convenience sampling method was used. Point estimate and 95% Confidence Interval were calculated.

Results: Among 594 patients with urinary tract infections, the prevalence of multidrug resistant Escherichia coli was 102 (17.17%) (14.14-20.20, 95% Confidence Interval). Out of which, the production of extended-spectrum beta-lactamase and AmpC beta-lactamase were observed in 74 (72.54%), and 28 (27.45%) isolates respectively. The co-production of extended-spectrum beta-lactamases/AmpC was observed in 17 (16.67%).

Conclusions: The prevalence of multidrug resistant Escherichia coli among patients urinary samples of patient with urinary tract infection was lower as compared to the other studies done in similar settings.

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Published

2023-05-01

How to Cite

Chaudhary, R. ., Pradhan, M., Bhatta, S., Shrestha, S. ., Adhikari, N. ., & Singh, Y. I. (2023). Multidrug Resistant Escherichia coli among Urinary Samples of Patients with Urinary Tract Infection in the Microbiology Department of a Tertiary Care Center: A Descriptive Cross-Sectional Study. Journal of Nepal Medical Association, 61(261), 437–441. https://doi.org/10.31729/jnma.8160

Issue

Vol. 61 No. 261 (2023): JNMA: Published Monthly

Section

Original Article

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Copyright (c) 2023 Raina Chaudhary

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