RETROSPECTIVE ANALYSIS OF BREAST CANCER CASES AND SURGICAL TREATMENT IN A PERIOD OF TEN YEARS

Abstract

Retrospective analysis of 321 cases of breast cancer diagnosed in T. U Teaching Hospital
in a period of 10 years, from May, 1991 to April, 2000 was carried out. There were
317 cases (98.8%) females and 4 cases males (1.2%). The youngest patient was 22
year old female and oldest patient was 92 year old female. The most common age
group according to frequency was in forties (34.6%) followed by in thirties (25.5 %).
Mean duration of symptoms before coming to doctor was 8.3 months and mean size of
tumor was 6 cm. Out of 317 females, 310(97.2%) were married and average number
of children was 3. Out of 289 cases diagnosed as malignancy with fine needle aspiration
cytology (FNAC) 279 (96.5%) was also diagnosed as malignancy in biopsy and the
remaining 10 cases as non malignant diseases were diagnosed as malignancy in biopsy
with a false negative rate of 3.5%. The histological types of breast cancer cases were
Infiltrating Ductal Carcinoma 280 cases (87.2%), Medullary Carcinoma 11 cases
(3.4%), Infiltrating Lobular Carcinoma 5 cases (1.6%), Mucinous Carcinoma 4 cases
(1.2%), Sarcoma 4 cases (1.2%), Squamous Cell Carcinoma 4 cases (1.2%), Papillary
Carcinoma 3 cases (0.9%), Tubular Carcinoma 2 cases, Adenosquamous Carcinoma
2 cases (0.6%), Intraductal Carcinoma 2 cases (0.6%) and Non-Hodgkins Lymphoma
1 case. Out of 305 operated cases, the types of operation performed was Modified
Radical Mastectomy in 208 cases (68 %) and palliative mastectomy in 72 cases (23.5%),
only lumpectomy in 24 cases (7.9%) and others in 2 cases. Among 246 cases with
available axillary lymph node biopsy, there was metastatic diseases in 146 cases (60%)
of cases. The Breast cancer was diagnosed in advanced stages in 63% of cases. Stage
IIIA (24%), Stage IIIB (21.5%) and Stage IV (17.4%). Breast cancers were diagnosed
in advanced stages in below 40 age group in 65 out of 90 cases (72.2 % ) compared
to137 out of 231 cases ( 59.3 % ) in above 40 age group.
Key Words: Breast cancer, Advanced stage, FNAC, Surgery.