TY - JOUR AU - Thapa, Lekhjung AU - Pokhrel, Baburam AU - Shrestha, Asis AU - Pradhan, Manohar AU - Bhandari, Tirtha Raj AU - Shrestha, Shakti AU - Poudel, Ramesh Sharma AU - Poudel, Raju PY - 2014/09/30 Y2 - 2024/03/29 TI - Status of Vitamin D and its Association with Stroke Risk Factors in Patients with Acute Ischemic Stroke in a Tertiary Care Hospital JF - Journal of Nepal Medical Association JA - J Nepal Med Assoc VL - 52 IS - 195 SE - Original Article DO - 10.31729/jnma.2719 UR - http://jnma.com.np/jnma/index.php/jnma/article/view/2719 SP - 935-939 AB - <p><strong>Introduction:</strong> Vitamin D deficiency has been associated with many neurological illnesses. The status of Vitamin D in Nepalese ischemic stroke patients is still unknown. This study aims to assess the status of vitamin D and its association with stroke risk factors in patients with acute ischemic stroke from Central Nepal.</p><p><strong>Methods:</strong> A total of 60 patients with ischemic stroke were included in the study. Their clinical profile and Vitamin D status were assessed. Frequency distribution, Pearson χ2test and Kruskal-Wallis test were performed for statistical analysis using SPSS-IBM 20.</p><p><strong>Results:</strong> The median (IQR) age of the patient was 65 (53.25, 70.75) years, ranging from 18-87 years. Thirty-four (56.7%) were males. Fourty-eight (80%) patients had hypertension and 34 (56.7%) were smoker. Previous stroke was present in six (10%) cases. Thirty-seven (61.6%) patients had low levels of Vitamin D out of which 26 (43.3%) had vitamin D insufficiency and 11 (18.3%) had vitamin D deficiency. Vitamin D level was significantly associated with previous history of stroke (P=0.043).</p><p><strong>Conclusions:</strong> Vitamin D deficiency occurs in patients with ischemic stroke. Previous episodes of stroke with low vitamin D levels could be a cause of recurrent strokes. Further studies are necessary to establish the role of vitamin D in acute ischemic stroke in Nepalese population.</p><div data-canvas-width="77.505"><strong>Keywords:</strong> deficiency; nepal; stroke; vitamin D.</div> ER -