Hashimoto's Thyroiditis and Medullary Carcinoma of Thyroid

Authors

  • Senjuti Dasgupta Department of Pathology, Medical College, Kolkata, West Bengal, India.
  • Sudipta Chakrabarti ESI PGIMSR, Manicktala, Kolkata, West Bangal, India.
  • Prakas Kumar Mandal IPGME&R, Kolkata, West Bangal, India.
  • Shikha Das RG Kar Medical College and Hospital, Kolkata, West Bengal, India.

DOI:

https://doi.org/10.31729/jnma.2761

Keywords:

association, hashimoto’s thyroiditis, histopathology, medullary carcinoma of thyroid.

Abstract

Hashimoto’s thyroiditis has been found to be associated with lymphoma, papillary carcinoma and Hürthle cell neoplasms of thyroid. In contrast, there are only a few reports of co-existence of HT with medullary carcinoma of thyroid. An overall prevalence of medullary carcinoma of only 0.35% has been reported in HT patients. Such a rare combination is being presented here. A 33 year old female presented with history of goiter for one year. Fine needle aspiration cytology of the swelling revealed cytological features suggestive of medullary carcinoma of thyroid. Histopathological examination of total thyroidectomy specimen revealed Hashimoto’s thyroiditis along with medullary carcinoma of thyroid. Although Hashimoto’s thyroiditis can uncommonly coexist with thyroid neoplasm, its association with medullary carcinoma is extremely rare and hence being presented. 

Keywords: association, hashimoto’s thyroiditis, histopathology, medullary carcinoma of thyroid.

References

Rosai J, Ackerman. Thyroid gland. In: Rosai J,Ackerman,
editors. Rosai and Ackerman’s surgical pathology. 10th ed.
St. Louis: Elsevier; 2011. p. 488–564.
3. Weiss LM, Weinberg DS, Warhol MJ. Medullary carcinoma
arising in a thyroid with Hashimoto's disease. Am J Clin
Pathol. 1983;80:534-8.
4. Gaskin D, Parai SK, Parai MR. Hashimoto's thyroiditis with
medullary carcinoma. Can J Surg. 1992;35:528-30.
5. De Pasquale L, Sommaruga L, Andreani S, Bastagli A.
Hashimoto's thyroiditis and medullary carcinoma in
the same gland: a purelyrandom occurrence? Chir Ital.
2004;56:557-62.
6. Mousa U, Gursoy A, Ozdemir H, Moray G. Medullary
thyroid carcinoma in a patient with Hashimoto's thyroiditis
diagnosed by calcitonin washout from a thyroid nodule.
Diagn Cytopathol. 2013;41:644-6.
7. Schuetz M, Beheshti M, Oezer S, Novotny C, Paul M, Hofmann
A, et al. Calcitonin measurements for early detection of
medullary thyroid carcinoma or its premalignant conditions
in Hashimoto's thyroiditis. Anticancer Res. 2006;26:723-7.
8. Büyükaşık O, Hasdemir AO, Yalçın E, Celep B, Sengül
S, Yandakçı K, et al. The association between thyroid
malignancy and chronic lymphocytic thyroiditis: should it
alter the surgical approach? Endokrynol Pol. 2011;62:303-8.
9. Cordioli MI, Cury AN, Nascimento AO, de Oliveira
AK, Mello M, Saieg MA. Study of the histological profile of
papillary thyroid carcinomas associated with Hashimoto's
thyroiditis. Arq Bras Endocrinol Metabol. 2013;57:445-9.
10. Reda G, Cesareo R, Lolli E, Gargiulo A. Thyroid cancer and
Hashimoto's thyroiditis. Minerva Chir. 1997;52:139-41.
11. Dayan CM, Daniels GH. Chronic autoimmune thyroiditis. N
Engl J Med. 1996;335:99-107.

Downloads

How to Cite

Dasgupta, S., Chakrabarti, S., Mandal, P. K., & Das, S. (2014). Hashimoto’s Thyroiditis and Medullary Carcinoma of Thyroid. Journal of Nepal Medical Association, 52(194), 831–833. https://doi.org/10.31729/jnma.2761

Issue

Vol. 52 No. 194 (2014)

Section

Case Reports

License

JNMA allow to read, download, copy, distribute, print, search, or link to the full texts of its articles and allow readers to use them for any other lawful purpose. The author(s) are allowed to retain publishing rights without restrictions. The JNMA work is licensed under a Creative Commons Attribution 4.0 International License. More about Copyright Policy.