Anti-leucine-rich Glioma-inactivated-1 Encephalitis with Faciobrachial Dystonic Seizures and Behavioral Problems: A Case Report

Authors

  • Ayush Adhikari Department of Medicine, Shree Birendra Hospital, Chhauni, Kathmandu, Nepal
  • Ram Chandra Subedi Department of Medicine, Shree Birendra Hospital, Chhauni, Kathmandu, Nepal
  • Subi Acharya Department of Medicine, Shree Birendra Hospital, Chhauni, Kathmandu, Nepal
  • Raju Paudel Department of Medicine, Shree Birendra Hospital, Chhauni, Kathmandu, Nepal

DOI:

https://doi.org/10.31729/jnma.5008

Keywords:

autoimmune, case report, limbic, seizure

Abstract

Anti-Leucine-rich glioma-inactivated-1 encephalitis is a subtype of autoimmune encephalitis
characterized by cognitive impairment, faciobrachial dystonic seizures, and behavioural changes.
There is no reported case from Nepal. We report a case of a 54-year old male who presented with
abnormal body movement, behavioural changes, rapid eye movement sleep behavioural changes,
and cognitive decline. Investigations revealed magnetic resonance imaging findings of fluidattenuated inversion recovery intensity signal in bilateral temporal lobes with anti-leucine-rich
glioma-inactivated-1 antibody in serum leading to diagnosis of anti-leucine-rich glioma-inactivated-1
encephalitis. He was treated with steroids and intravenous immunoglobulin. Timely diagnosis is
vital to prevent complications and improve outcomes.

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Published

2020-07-31

How to Cite

Adhikari, A., Subedi, R. C. ., Acharya, S. ., & Paudel, R. (2020). Anti-leucine-rich Glioma-inactivated-1 Encephalitis with Faciobrachial Dystonic Seizures and Behavioral Problems: A Case Report. Journal of Nepal Medical Association, 58(227), 487–490. https://doi.org/10.31729/jnma.5008

Issue

Vol. 58 No. 227 (2020): JNMA: Published Monthly

Section

Case Reports

License

Copyright (c) 2020 Ayush Adhikari, Ram Chandra Subedi, Subi Acharya, Raju Paudel

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