Clinical Profile and Complications Experienced by Chronic Kidney Disease Patients undergoing Hemodialysis in a Tertiary Hospital of Nepal: An Observational Study

Abstract

Introduction: Chronic kidney disease is emerging public health problems globally. Hemodialysis is the commonest treatment modality but it causes some complications and fluctuation in parameters. This study aimed to assess the clinical profile and complications experienced by chronic kidney disease patients undergoing hemodialysis.

Methods: This was an observational study conducted from December, 2023 to February, 2024 Patients aged 20 and above, receiving hemodialysis more than three months were included in the study. Descriptive analysis was done.

Results: Among 110 CKD patients undergoing hemodialysis, 62 (56.36%) were 50 years of age or younger, with a mean 48.76±13.365. The study population included 66 (60%) male and mean age of the patients was 48.76±13.36. In this study group 90 (81.82%) had two session of dialysis per week. Mean Pre-HD systolic blood pressure was 150.64±23.95 mmHg and Post-HD was 147.64±24.38 mmHg. In this study the mean hemoglobin was 9.38±1.85 gm/dl, glucose was 110.85±46.62 mg/ dl, urea 91.81±37.73 mg/dl and creatinine 7.94±2.68 mg/dl. In the patient population undergoing dialysis oliguria was observed in 106 (96.36%), weakness 98 (89.09%) and insomnia was observed in 87 (79.09%).

Conclusions: In this study, more than half of the patient were in the age group of less than or equal to 50 years. Common symptoms included reduced urine output, weakness, and insomnia. Hypertension was the most common underlying condition, often occurring with diabetes.